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RADIATION THERAPY ONCOLOGY GROUP

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RTOG 0126

A PHASE III RANDOMIZED STUDY OF HIGH DOSE 3D-CRT VERSUS STANDARD DOSE 3D-CRT IN PATIENTS TREATED FOR LOCALIZED PROSTATE CANCER    (Closed to patient accrual as of 8/20/08.)

RTOG 0232

A PHASE III STUDY COMPARING COMBINED EXTERNAL BEAM RADIATION AND TRANSPERINEAL INTERSTITIAL PERMANENT BRACHYTHERAPY WITH BRACHYTHERAPY ALONE FOR SELECTED PATIENTS WITH INTERMEDIATE RISK PROSTATIC CARCINOMA

NSABP B-39/ RTOG 0413

A RANDOMIZED PHASE III STUDY OF CONVENTIONAL WHOLE BREAST IRRADIATION (WBI) VERSUS PARTIAL BREAST IRRADIATION (PBI) FOR WOMEN WITH STAGE 0, I, OR II BREAST CANCER

RTOG 0415

A PHASE III RANDOMIZED STUDY OF HYPOFRACTIONATED 3D-CRT/IMRT VERSUS CONVENTIONALLY FRACTIONATED 3D-CRT/IMRT IN PATIENTS WITH FAVORABLE-RISK PROSTATE CANCER

RTOG 0418

A PHASE II STUDY OF INTENSITY MODULATED RADIATION THERAPY (IMRT) TO THE PELVIS +/- CHEMOTHERAPY FOR POST-OPERATIVE PATIENTS WITH EITHER ENDOMETRIAL OR CERVICAL CARCINOMA

RTOG 0436

A PHASE III TRIAL EVALUATING THE ADDITION OF CETUXIMAB TO PACLITAXEL, CISPLATIN, AND RADIATION FOR PATIENTS WITH ESOPHAGEAL CANCER WHO ARE TREATED WITHOUT SURGERY

RTOG 0438

A PHASE I TRIAL OF HIGHLY CONFORMAL RADIATION THERAPY FOR PATIENTS WITH LIVER METASTASES

RTOG 0521

A PHASE III PROTOCOL OF ANDROGEN SUPPRESSION (AS) AND 3DCRT/IMRT VS. AS AND 3DCRT/IMRT FOLLOWED BY CHEMOTHERAPY WITH DOCETAXEL AND PREDNISONE FOR LOCALIZED, HIGH-RISK PROSTATE CANCER

RTOG 0522

A RANDOMIZED PHASE III TRIAL OF CONCURRENT ACCELERATED RADIATION AND CISPLATIN VERSUS CONCURRENT ACCELERATED RADIATION, CISPLATIN, AND CETUXIMAB (C225) [FOLLOWED BY SURGERY FOR SELECTED PATIENTS] FOR STAGE III AND IV HEAD AND NECK CARCINOMAS

RTOG 0526

A PROSPECTIVE PHASE II TRIAL OF TRANSPERINEAL ULTRASOUND-GUIDED BRACHYTHERAPY FOR LOCALLY RECURRENT PROSTATE ADENOCARCINOMA FOLLOWING EXTERNAL BEAM RADIOTHERAPY

RTOG 0534

A PHASE III TRIAL OF SHORT TERM ANDROGEN DEPRIVATION WITH PELVIC LYMPH NODE OR PROSTATE BED ONLY RADIOTHERAPY (SPORT) IN PROSTATE CANCER PATIENTS WITH A RISING PSA AFTER RADICAL PROSTATECTOMY

RTOG 0539

PHASE II TRIAL OF OBSERVATION FOR LOW-RISK MENINGIOMAS AND OF RADIOTHERAPY FOR INTERMEDIATE- AND HIGH-RISK MENINGIOMAS

RTOG 0615

A PHASE II STUDY OF CONCURRENT CHEMORADIOTHERAPY USING THREE-DIMENSIONAl CONFORMAL RADIOTHERAPY (3D CRT) OR INTENSITY-MODULATED RADIATION ThERAPY (IMRT) + BEVACIZUMAB (BV) FOR LOCALLY OR REGIONALLY ADVANCED NASOPHARYNGEAL CANCER

RTOG 0617

A RANDOMIZED PHASE III COMPARISON OF STANDARD-DOSE (60 Gy) VERSUS HIGHDOSE (74 Gy) CONFORMAL RADIOTHERAPY WITH CONCURRENT AND CONSOLIDATION CARBOPLATIN/PACLITAXEL +/- CETUXIMAB (IND #103444) IN PATIENTS WITH STAGE IIIA/IIIB NON-SMALL CELL LUNG CANCER

RTOG 0618

A PHASE II TRIAL OF STEREOTACTIC BODY RADIATION THERAPY (SBRT) IN THE TREATMENT OF PATIENTS WITH OPERABLE STAGE I/II NON-SMALL CELL LUNG CANCER

RTOG 0619

A RANDOMIZED PHASE II TRIAL OF CHEMORADIOTHERAPY VERSUS CHEMORADIOTHERAPY AND VANDETANIB FOR HIGH-RISK POSTOPERATIVE ADVANCED SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK

RTOG 0621

ADJUVANT 3DCRT/IMRT IN COMBINATION WITH ANDROGEN SUPPRESSION AND DOCETAXEL FOR HIGH RISK PROSTATE CANCER PATIENTS POST-PROSTATECTOMY: A PHASE II TRIAL

RTOG 0622

A PHASE I/II TRIAL OF SAMARIUM-153 FOLLOWED BY SALVAGE PROSTATIC FOSSA IRRADIATION IN HIGH-RISK, CLINICALLY NON-METASTATIC PROSTATE CANCER AFTER RADICAL PROSTATECTOMY

RTOG 0623

A PHASE II TRIAL OF COMBINED MODALITY THERAPY WITH GROWTH FACTOR SUPPORT FOR PATIENTS WITH LIMITED STAGE SMALL CELL LUNG CANCER

RTOG 0630

A PHASE II TRIAL OF IMAGE GUIDED PREOPERATIVE RADIOTHERAPY FOR PRIMARY SOFT TISSUE SARCOMAS OF THE EXTREMITY

RTOG 0631

PHASE II/III STUDY OF IMAGE-GUIDED RADIOSURGERY/SBRT FOR LOCALIZED SPINE METASTASIS

RTOG 0712

A PHASE II RANDOMIZED STUDY FOR PATIENTS WITH MUSCLE-INVASIVE BLADDER CANCER EVALUATING TRANSURETHRAL SURGERY AND CONCOMITANT CHEMORADIATION BY EITHER BID IRRADIATION PLUS 5-FLOUROURACIL AND CISPLATIN OR QD IRRADIATION PLUS GEMCITABINE FOLLOWED BY SELECTIVE BLADDER PRESERVATION AND GEMCITABINE/CISPLATIN ADJUVANT CHEMOTHERAPY

RTOG 0724

PHASE III RANDOMIZED STUDY OF CONCURRENT CHEMOTHERAPY AND PELVIC RADIATION THERAPY WITH OR WITHOUT ADJUVANT CHEMOTHERAPY IN HIGH-RISK PATIENTS WITH EARLY-STAGE CERVICAL CARCINOMA FOLLOWING RADICAL HYSTERECTOMY

RTOG 0813

SEAMLESS PHASE I/II STUDY OF STEREOTACTIC LUNG RADIOTHERAPY (SBRT) FOR EARLY STAGE, CENTRALLY LOCATED, NON-SMALL CELL LUNG CANCER (NSCLC) IN MEDICALLY INOPERABLE PATIENTS

RTOG 0815

A PHASE III PROSPECTIVE RANDOMIZED TRIAL OF DOSE-ESCALATED RADIOTHERAPY WITH OR WITHOUT SHORT-TERM ANDROGEN DEPRIVATION THERAPY FOR PATIENTS WITH INTERMEDIATE-RISK PROSTATE CANCER

RTOG 0822

A PHASE II EVALUATION OF PREOPERATIVE CHEMORADIOTHERAPY UTILIZING INTENSITY MODULATED RADIATION THERAPY (IMRT) IN COMBINATION WITH CAPECITABINE AND OXALIPLATIN FOR PATIENTS WITH LOCALLY ADVANCED RECTAL CANCER

RTOG 0825

PHASE III DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL OF CONVENTIONAL CONCURRENT CHEMORADIATION AND ADJUVANT TEMOZOLOMIDE PLUS BEVACIZUMAB VERSUS CONVENTIONAL CONCURRENT CHEMORADIATION AND ADJUVANT TEMOZOLOMIDE IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA

RTOG 0837

RANDOMIZED, PHASE II, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF CONVENTIONAL CHEMORADIATION AND ADJUVANT TEMOZOLOMIDE PLUS CEDIRANIB VERSUS CONVENTIONAL CHEMORADIATION AND ADJUVANT TEMOZOLOMIDE PLUS PLACEBO IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA

RTOG 0839

RANDOMIZED PHASE II STUDY OF PRE-OPERATIVE CHEMORADIOTHERAPY +/- PANITUMUMAB (IND #110152) FOLLOWED BY CONSOLIDATION CHEMOTHERAPY IN POTENTIALLY OPERABLE LOCALLY ADVANCED (STAGE IIIA, N2+) NON-SMALL CELL LUNG CANCER

RTOG 0848

A PHASE III TRIAL EVALUATING BOTH ERLOTINIB AND CHEMORADIATION AS ADJUVANT TREATMENT FOR PATIENTS WITH RESECTED HEAD OF PANCREAS ADENOCARCINOMA

RTOG 0912

A RANDOMIZED PHASE II STUDY OF CONCURRENT INTENSITY MODULATED RADIATION THERAPY (IMRT), PACLITAXEL AND PAZOPANIB (NSC 737754)/PLACEBO, FOR THE TREATMENT OF ANAPLASTIC THYROID CANCER

RTOG 0913

PHASE I/II TRIAL OF CONCURRENT RAD001 (EVEROLIMUS) WITH TEMOZOLOMIDE/RADIATION FOLLOWED BY ADJUVANT RAD001/TEMOZOLOMIDE IN NEWLY DIAGNOSED GLIOBLASTOMA

RTOG 0915/
NCCTG N0927

A RANDOMIZED PHASE II STUDY COMPARING 2 STEREOTACTIC BODY RADIATION THERAPY (SBRT) SCHEDULES FOR MEDICALLY INOPERABLE PATIENTS WITH STAGE I PERIPHERAL NON-SMALL CELL LUNG CANCER

RTOG 0920

A PHASE III STUDY OF POSTOPERATIVE RADIATION THERAPY (IMRT) +/- CETUXIMAB FOR LOCALLY-ADVANCED RESECTED HEAD AND NECK CANCER

RTOG 0921

A PHASE II STUDY OF POSTOPERATIVE INTENSITY MODULATED RADIATION THERAPY (IMRT) WITH CONCURRENT CISPLATIN AND BEVACIZUMAB FOLLOWED BY CARBOPLATIN AND PACLITAXEL FOR PATIENTS WITH ENDOMETRIAL CANCER

RTOG 0924

ANDROGEN DEPRIVATION THERAPY AND HIGH DOSE RADIOTHERAPY WITH OR WITHOUT WHOLE-PELVIC RADIOTHERAPY IN UNFAVORABLE INTERMEDIATE OR FAVORABLE HIGH RISK PROSTATE CANCER: A PHASE III RANDOMIZED TRIAL

RTOG 0926

A PHASE II PROTOCOL FOR PATIENTS WITH STAGE T1 BLADDER CANCER TO EVALUATE SELECTIVE BLADDER PRESERVING TREATMENT BY RADIATION THERAPY CONCURRENT WITH CISPLATIN CHEMOTHERAPY FOLLOWING A THOROUGH TRANSURETHRAL SURGICAL RE-STAGING

RTOG 0933

A PHASE II TRIAL OF HIPPOCAMPAL AVOIDANCE DURING WHOLE BRAIN RADIOTHERAPY FOR BRAIN METASTASES

RTOG 0937

RANDOMIZED PHASE II STUDY COMPARING PROPHYLACTIC CRANIAL IRRADIATION ALONE TO PROPHYLACTIC CRANIAL IRRADIATION AND CONSOLIDATIVE EXTRA-CRANIAL IRRADIATION FOR EXTENSIVE DISEASE SMALL CELL LUNG CANCER (ED-SCLC)

RTOG 0938

A RANDOMIZED PHASE II TRIAL OF HYPOFRACTIONATED RADIOTHERAPY FOR FAVORABLE RISK PROSTATE CANCER

RTOG 1005

A PHASE III TRIAL OF ACCELERATED WHOLE BREAST IRRADIATION WITH HYPOFRACTIONATION PLUS CONCURRENT BOOST VERSUS STANDARD WHOLE BREAST IRRADIATION PLUS SEQUENTIAL BOOST FOR EARLY-STAGE BREAST CANCER

RTOG 1008

PHASE II - ADJUVANT CONCURRENT RADIATION AND CHEMOTHERAPY VS RADIATION ALONE IN RESECTED HIGH-RISK MALIGNANT SALIVARY GLAND TUMORS

RTOG 1010

A PHASE III TRIAL EVALUATING THE ADDITION OF TRASTUZUMAB TO TRIMODALITY TREATMENT OF HER2-OVEREXPRESSING ESOPHAGEAL ADENOCARCINOMA

RTOG 1012

PHASE II RANDOMIZED TRIAL OF PROPHYLACTIC MANUKA HONEY FOR THE REDUCTION OF CHEMORADIATION THERAPY INDUCED ESOPHAGITIS-RELATED PAIN DURING THE TREATMENT OF LUNG CANCER

RTOG 1014

PHASE II STUDY OF REPEAT BREAST PRESERVING SURGERY AND 3D-CONFORMAL PARTIAL BREAST RE-IRRADIATION (PBRI) FOR LOCAL RECURRENCE OF BREAST CARCINOMA

RTOG 1016

PHASE III TRIAL OF RADIOTHERAPY PLUS CETUXIMAB VERSUS CHEMORADIOTHERAPY IN HPV-ASSOCIATED OROPHARYNX CANCER

ACOSOG Z4099
RTOG 1021

RANDOMIZED PHASE III STUDY OF SUBLOBAR RESECTION (+/- BRACHYTHERAPY) VERSUS STEREOTACTIC BODY RADIAT ION THERAPY IN HIGH RISK PATIENTS WITH STAGE I NON-SMALL CELL LUNG CANCER (NSCLC)

RTOG 1102

A PHASE I STUDY OF INDUCTION GANITUMAB (IND #113278) AND GEMCITABINE, FOLLOWED BY GANITUMAB, CAPECITABINE, AND 3D-CONFORMAL RADIATION THERAPY (3D-CRT) WITH SUBSEQUENT MAINTENANCE THERAPY FOR LOCALLY ADVANCED PANCREATIC CANCER

RTOG 1106

RANDOMIZED PHASE II TRIAL OF INDIVIDUALIZED ADAPTIVE RADIOTHERAPY USING DURING-TREATMENT FDG-PET/CT AND MODERN TECHNOLOGY IN LOCALLY ADVANCED NON-SMALL CELL LUNG CANCER (NSCLC)

RTOG 1112

RANDOMIZED PHASE III STUDY OF SORAFENIB VERSUS STEREOTACTIC BODY RADIATION THERAPY FOLLOWED BY SORAFENIB IN HEPATOCELLULAR CARCINOMA

RTOG 1115

PHASE III TRIAL OF DOSE ESCALATED RADIATION THERAPY AND STANDARD ANDROGEN DEPRIVATION THERAPY (ADT) WITH A GNRH AGONIST VS. DOSE ESCALATED RADIATION THERAPY AND ENHANCED ADT WITH A GNRH AGONIST AND TAK-700 FOR MEN WITH HIGH RISK PROSTATE CANCER

RTOG 1203

A RANDOMIZED PHASE III STUDY OF STANDARD VS. IMRT PELVIC RADIATION FOR POST-OPERATIVE TREATMENT OF ENDOMETRIAL AND CERVICAL CANCER (TIME-C)--RTOG CCOP STUDY

RTOG 1205

RANDOMIZED PHASE II TRIAL OF CONCURRENT BEVACIZUMAB AND RE-IRRADIATION VERSUS BEVACIZUMAB ALONE AS TREATMENT FOR RECURRENT GLIOBLASTOMA

RTOG 1216

RANDOMIZED PHASE II/III TRIAL OF SURGERY AND POSTOPERATIVE RADIATION DELIVERED WITH CONCURRENT CISPLATIN VERSUS DOCETAXEL VERSUS DOCETAXEL AND CETUXIMAB FOR HIGH-RISK SQUAMOUS CELL CANCER OF THE HEAD AND NECK

NSABP B-51/ RTOG 1304

A RANDOMIZED PHASE III CLINICAL TRIAL EVALUATING POST-MASTECTOMY CHESTWALL AND REGIONAL NODAL XRT AND POST-LUMPECTOMY REGIONAL NODAL XRT IN PATIENTS WITH POSITIVE AXILLARY NODES BEFORE NEOADJUVANT CHEMOTHERAPY WHO CONVERT TO PATHOLOGICALLY NEGATIVE AXILLARY NODES AFTER NEOADJUVANT CHEMOTHERAPY

Repeat Credentialing for RTOG Advanced Technology Protocols  6/19/2009

IGRT Credential Process for RTOG Protocols

RTOG Protocols Closed to Accrual

RTOG Protocols in Development  (requires password)